fertility preservation

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fertility preservation

 


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Fertility Preservation - Publications

 

Scientific Books and Chapters:

Fertility Preservation

Azim A & Oktay K. Frontiers in Fertility. In: Nezhat’s Operative Gynecologic Laparoscopy with Hysteroscopy. Nezhat C, Nezhat F, Nezhat C (Eds.). Cambridge University Press, 2007. In press. 

Oktay K & Sonmezer M. Fertility Issues and Options in Young Women With Cancer. In: Recent Results in Cancer Research – Cancer and Pregnancy. Survone, Pavlidis (Eds.) In press.

Oktay K, Reinecke J, Nohr-Beck L. (eds and authors). Fertility & Cancer in 101 Questions, 2007. In press. 

Oktay K. Ovarian Transplantation. In: An Atlas of Gynecologic Oncology. Smith JR, Del Priore G, Curtin J & Monaghan J (eds). In press.

Sonmezer M. & Oktay K. Preservation of Fertility in Patients Undergoing Cytotoxic Therapy, Uptodate.com, Version 14.1, Robert L. Barbieri, editor, 2006.

Oktay K, & Buyuk E. Fertility and Cancer in Women.  In: Reproductive Medicine Secrets. Chan P, Goldshein M, Rosenwaks Z (eds). Hanley & Belfus, Inc., 2004;380-384.

Oktem O, Sonmezer M & Oktay K. Ovarian Cryopreservation and Transplantation.  In:  Textbook of Assisted Reproductive Technology and Clinical Perspectives.  Gardner DK, Weissman A, Howles CM, Shoham Z (eds). Taylor & Francis, London, UK:2004;315-327. 

Sonmezer M & Oktay K. Fertility Preservation in female cancer patients: A comprehensive approach. In: Textbook of Fertility Preservation.  Tulandi & Gosden (eds). Taylor & Francis. London, UK; 2004; 177-190.

Oktay K,  & Buyuk E. The technique of ovarian transplantation: Laboratory and clinical aspects. In: A color atlas for human assisted reproduction: Laboratory & clinical insights. Patrizio P, Guelman V, Tucker M (eds). Lippincot, 2003; 229-240.

Oktay K.  Ovarian Cryopreservation and Transplantation. In: Textbook of Assisted Reproductive Technology and Clinical Perspectives. Gardner DK, Weissman A, Howles CM, Shoham Z (eds). Martin Dunitz Limited. London, UK: 2001; 279-284.

Oktay K, Karlikaya G, Bayrakceken A.  New strategies in studying ovarian aging.  In:  Biology of Menopause.  Bellini F (ed).  Springer-Verlac, NY: 2000; 80-88.

Oktay K, and Gosden RG.  Cryopreservation of oocytes and ovarian tissue.  In:  A textbook of in vitro fertilization and assisted reproduction, Brinsden PR, editor. The Parthenon Publishing Co. Lancaster, UK: 1999; 303-310.

 

Scientific Manuscripts:

 

Oktay K. Integrin Beta-4 Signaling Plays a Key Role in Mouse Embryogenesis. Reproductive Sciences 2008 August 23 [In Press].

Oktay K, Sönmezer M. Gonadotropin-releasing hormone analogs in fertility preservation-lack of biological basis? Nat Clin Pract Endocrinol Metab. 2008 Jul 15; [Epub ahead of print] PMID: 18628732

Azim A, Costantini-Ferrando, Oktay K. Safety of Fertility Preservation by Ovarian Stimulation with Letrozole and Gonadotropins in Breast cancer Patients: A prospective controlled study. J Clin Oncol 2008 June 1;26(16):2630-5.

Sonmezer M, Bang H, Oktay K. Can GnRH analogues preserve gonadal function without preserving fertility? Oncologist 2008 May; 13(5):615-7.

Oktay K & Cil AP. Who is the Best Candidate for Oocyte Cryopreservation Research. Fertil Steril 2008 Apr 26[Epub ahead of print].

Oktay K, Buyuk E, Öktem Ö, Oktay M, Giancotti F. Jun Amino Terminal Kinase Regulates G2/M Transition Through A Mechanism Upstream of Aurora-B. Cell Cycle2008 Feb 15; 7(4); 533-541 [Epub ahead of print].

Oktem O, Oktay K. Stem cells: a perspective on oocytes. Ann N Y Acad Sci 2008 Apr; 1127:20-6.

Oktem O, Oktay K. The Ovary: Anatomy and Function Throughout Human Life. Ann NY Acad Sci 2008
Apr;1127:1-9.

Azim A, Costantini-Ferrando, Oktay K. Safety of Fertility Preservation by Ovarian Stimulation with Letrozole and Gonadotropins in Breast cancer Patients: A prospective controlled study. J Clin Oncol 2008.

Reh A, Oktem O, Oktay K. Impact of breast cancer chemotherapy on ovarian reserve: a prospective observational analysis by menstrual history and ovarian reserve markers. Fertil Steril. 2007 Dec 29.

Oktay K, Sönmezer M. Fertility issues and options in young women with cancer. Recent Results Cancer Res. 2008;178:203-24. 

Oktay K & Meirow D. Effects of Cancer Therapy on Fertility and Reproduction. Sexuality, Reproduction and Menopause, 2007 5(1):17-21.

Öktem Ö and Oktay K. A Novel Ovarian Xenografting Model to Characterize the Impact of Chemotherapy Agents on Human Primordial Follicle Reserve. Cancer Res. 2007 Nov 1; 67(21): 10159-61. 

Öktem Ö and Oktay K.  Quantitative Assessment of the Impact of Chemotherapy on Ovarian Follicle Reserve and Stromal Function. Cancer. 2007 Oct 11; 110(10): 2222-2229.

Oktay  K, Sönmezer  M, Öktem Ö, Fox  K, Emons G, Bang H. Absence Of The Conclusive Evidence For The Safety And Efficacy Of The Gonadotropin Releasing Hormone Analog Treatment In Protecting Against Chemotherapy-Induced Gonadal Injury. Oncologist. 2007 Sep; 12(9): 1056-66. 

Oktay K and Sönmezer M. Fertility Preservation in Gynecologic Cancers. Curr Opin Oncol. 2007 Sep; 19(5): 506-11.

Oktay K and Oktem Ö. Regeneration of Ooocytes Post-chemotherapy: Connecting the Evidence from Mouse to Human. J Clin Oncol 2007 Aug 1;25(22):3185-7.  

Oktay K, Demirtas E, Son W-Y, Lostritto K, Chian R-C, Tan S-L. In Vitro Maturation Of Germinal Vesicle Oocytes Recovered Post-Premature LH Surge: Description Of A Novel Approach To Fertility Preservation. Fertil Steril, 2007 May 19.

Azim A & Oktay K. Letrozole for ovulation induction and fertility preservation by embryo cryopreservation in young women with endometrial carcinoma. Fertil Steril, 2007 Aprn9.

Oktay K, Azim A, Constantini-Ferando M, Lostritto K. Relative Potency of Anastrozole Versus Letrozole to Supress Estradiol in Breast Cancer Patients Undergoing Ovarian Stimulation Before IVF, J Clin Endocrinol Metab 2007 Mar 13.

Martin JR, Kodaman P, Oktay K, Taylor H. Ovarian Cryopreservation with Transposition of a Contralateral Ovary: A Combined Approach for Fertility Preservation in Women Receiving Pelvic Radiation. Fertil Steril. 2007 Jan; 87(1): 189. e5-7. Epub 2006 Nov 1.

Oktay K, Oktem O, Reh A, Vahdat L. Measuring the Impact of Chemotherapy on Fertility in Women with Breast Cancer. J Clin Oncol. 2006 Aug 20; 24(24): 4044-6.

Oktay K, Hourvitz A, Sahin G, Oktem O, Safro B, Cil A, Bang H. Letrozole Reduces Estrogen and Gonadotropin Exposure in Women with Breast Cancer Undergoing Ovarian Stimulation Before Chemotherapy.  J Clin Endocrinol Metab 2006 Oct; 91(10): 3885-90. Epub 2006 Aug 1.

Oktay K, Cil A, Bang H. The Efficiency of Oocyte Cryopreservation: A Meta-Analysis. Fertil Steril. 2006 Jul; 86(1): 70-80.

Oktay K. An Individualized Approach to Fertility Preservation in Women with Cancer. J Support Oncol.   2006 Apr; 4(4): 181-2, 184.

Lee SJ, Schover LR, Partridge AH, Patrizio P, Wallace WH, Hagerty K, Beck LN, Brennan LV, Oktay K. American Society of Clinical Oncology Recommendations on Fertility Preservation in Cancer Patients. J Clin Oncol. 2006 Jun 20; 24(18): 2917-31. Epub May 1.

Oktay, K.  Spontaneous conceptions and live birth after heterotopic ovarian transplantation: is there a germline stem cell connection? Hum Reprod. 2006 Jun; 21(6): 1345-8.Epub 2006 Feb 3.

Sonmezer M & Oktay K. Fertility Preservation in Young Women Undergoing Breast Cancer Therapy. The Oncologist. 2006 May; 11(5): 422-34.

Oktay K. Options for preservation of fertility in women. N Engl J Med. 2005 Sep 29; 353(13): 1418-20.

Akar M & Oktay K. Restoration of ovarian endocrine function by ovarian transplantation. Trends Endocrinol Metab.2005 Oct; 16(8): 374-80.

Shamonki MI, Oktay K. Oocyte and ovarian tissue cyropreservation: indications, techniques, and applications.  Semin Reprod. Med. 2005 Aug; 23(3): 266-76.

Sonmezer M, Shamonki MI, Oktay K. Ovarian tissue cryopreservation: benefits and risks.  Cell Tissue Res. 2005 Oct; 322(1); 125-32. Epub 2005 Nov 3.

Oktay K. Further evidence on the safety and success of ovarian stimulation with Letrozole and Tamoxifen in breast cancer patients undergoing IVF to cryopreserve their embryos for fertility preservation. J Clin Oncol. 2005 Jun 1; 23(16): 3858-9.

Oktay K. Fertility preservation: an emerging discipline in the care of young patients with cancer. Lancet Oncol. 2005 Apr; 6(4): 192-3.

Oktay K. Successful human ovarian autotransplantation to the upper arm. Cancer. 2005 May; 103(9): 1982-3.

Roberts J & Oktay K. Fertility preservation: a comprehensive approach to the young woman with cancer. J Natl Cancer Inst Monogr. 2005;(34): 57-9.

Sonmezer M, Shamonki MI & Oktay K. Ovarian tissue cryopreservation: benefits and risks. Cell Tissue Res. 2005 Oct; 322(1): 125-32. Epub 2005 Nov 3.

Oktay K, Buyuk E, Libertella N, Akar M & Rosenwaks Z. Fertility preservation in breast cancer patients: a prospective comparison of ovarian stimulation with tamoxifen and letrozole for embryo cryopreservation. Jour Clin Oncol. 2005 Jul 1; 23(19): 4347-53.

Oktay K, & Tilly J. Live birth after cryopreserved ovarian tissue autotransplantation.  Lancet, 2004; Dec 11-17; 364(9451): 2091-2.

Anonymous; ASRM Practice Committee report on ovarian tissue and oocyte cryopreservation.  Fertil Steril, 2004; 82:993-998.

Sonmezer M & Oktay K. Fertility preservation in Female Cancer Patients. Human Reproduction Update. 2004 May-Jun; 10(3): 251-66. 

Oktay K, & Buyuk E. Ovarian transplantation in humans: indications, techniques and the risk of reseeding cancer. Eur J Obstet Gynecol Reprod Biol. 2004 Apr 5; 113 Suppl: S45-7.

Oktay K, Buyuk E, Veeck L, Zaninovic N, Xu K, Takeuchi T, Opsahl M & Rosenwaks Z.  Embryo development after heterotopic transplantation of cryopreserved ovarian tissue.  Lancet. March 13, 2004; 363(9412) 837-840. Epub 2004 March 9.

Oktay K, & Sonmezer M.  Fertility preservation, not just cryopreservation. human reprod. 2004 Mar; 19(3):477-80. Epub 2004 Jan 29.

Oktay K, Buyuk E, Rosenwaks Z, Rucinski J. A technique for transplantation of ovarian cortical strips to the forearm. Fertil Steril. 2003 Jul; 80(1):193-8.

Oktay K, Buyuk E, Davis O, Yermakova I, Veeck L, Rosenwaks Z. Fertility preservation in breast cancer patients: In vitro fertilization and embryo cryopreservation after ovarian stimulation with tamoxifen. Human Reprod 2003 Jan; 18(1):90-5.

Oktay K. Fertility preservation in female cancer patient, CME J Gynecol Oncol
2003; 8:139-142.

Oktay K,  & Buyuk, E. The potential of ovarian transplant to preserve fertility. Expert Opin Biol Ther. 2002 Apr; 2(4):361-70.

Oktay K. Evidence for limiting ovarian tissue harvesting for the purpose of ovarian transplantation to women younger than 40 years of age. J Clin Endocrinol Metab. 2002 Apr; 87(4): 1907-8.

Oktay K.  Autologous transplantation of whole ovaries vs. ovarian cortical strips.  JAMA 287: 44-45, 2002.

Oktay K. Ovarian Cryopreservation and transplantation: experience with the first five cases. Infert Reprod Med Clin N Am, 2002, 13:523-537.

Oktay K, & Yih M. Preliminary experience with orthotopic and heterotopic transplantation of ovarian cortical strips. Semin Reprod Med. 2002 Feb; 20(1):63-74.

Oktay K. Ovarian cryopreservation and transplantation: Preliminary findings and implications for cancer patients. Hum Reprod Update, 2001 Nov-Dec; 7:526-34.

Oktay K, Economos K, Rucinski J, Kan M, Veeck L, Rosenwaks Z. Endocrine function and oocyte retrieval after autologous transplantation of ovarian cortical pieces to the forearm. JAMA, 2001 Sep 26: 286:1490-1493.

Oktay K, Karlikaya G, Aydin B. A technique for laparoscopic transplantation of frozen-banked ovarian tissue. Fertil Steril. 2001 Jun; 75(6): 1212-6.

Oktay K, Kan M, Rosenwaks Z. Recent progress in oocyte and ovarian tissue cryopreservation. Curr Opin Obstet Gynecol. 2001 Jun; 13(3): 263-8.

Oktay K, Karlikaya G, Akman O, Ojakian G, Oktay M. Interaction of Extracellular Matrix and Activin-A in the initiation of follicle growth in the mouse. Biol Reprod.Aug 2000 Aug; 63(2):457-61.

Oktay K, and Karlikaya G.  Ovarian function after autologous transplantation of frozen-banked human ovarian tissue. N Engl J Med. 2000 Jun 22; 342(25): 1919.

Oktay K, Newton H, Gosden RG. Transplantation of cryopreserved human ovarian tissue results in follicle growth in SCID mice. Fertil Steril. 2000 Mar; 73(3): 599-603. 

Oktay K, Karlikaya G, Aydin BA. Ovarian tissue cryopreservation and transplantation: basic aspects. Mol Cell Endocrinol, 2000 Nov 27; 169(1-2): 105-108.

Oktay K, Newton H, Mullan J and Gosden R.  Development of human primordial follicles to antral stages in SCID/hpg mice stimulated with follicle stimulating hormone.  Human Reprod. 1998 May; 13(5): 1133-8.

Oktay K, Newton H, Aubard Y and Gosden RG: Cryopreservation of immature human oocytes and ovarian tissue: an emerging technology? Fertil Steril. 1998 Jan; 69(1):1-7.

Oktay K.  New horizons in assisted reproductive technologies. Assisted Reproduction Reviews, 8:51-54, 1998.

Oktay K, Nugent D, Newton H, Salha O, Chattergee P and Gosden R.  Isolation and characterization of primordial follicles from fresh and cryopreserved human ovarian tissue.  Fertil Steril. 1997 Mar; 67(3): 481-6.

Gosden RG, Oktay K, Radford JA and Rutherford AJ.  Ovarian tissue banking (CD-ROM).  Human Reproduction Update, 3:297, 1997.

Gosden RG, Oktay K, Mullan J and Jenner L:   In vitro maturation of human oocytes: Basic aspects.  Symposium on the ovary: Dysfunction and Treatment.  Excerpta Medica Int Cong Ser.  1106:149-158, 1996.

   

 

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